429 N Euclid Avenue, St Louis

Discover this iconic mixed-use opportunity in the heart of the Central West End—where refined residential living meets limitless commercial potential. Spanning four levels and accessible by both elevator and staircase, this architecturally striking property offers a seamless blend of sophistication and versatility.

A dramatic entry foyer introduces a gallery, boutique or restaurant space anchored by a private courtyard, complemented by a fitness studio and attached garage.

Beginning on the second floor, the penthouse residence is truly magazine-worthy, featuring an expansive great room, a commercial chef’s kitchen, breakfast room, wine cellar, bar, formal dining, and two bedrooms—including a serene primary suite with spa-inspired bath. Outdoor living is elevated with a private lap pool/spa and curated lounge spaces. The third level offers ultimate flexibility with a guest suite, office, or entertainment venue—complete with kitchenette and overhead door access to the outdoor pergola lounge, serving areas and private patios.

The finished lower level adds depth and character with stone walls, a spacious recreation room, kitchenette, two additional bedroom suites, a spa room, laundry, and abundant storage.

Equally suited as a private luxury residence, boutique hospitality concept, private club, or creative commercial venture—this is a rare Central West End offering designed for those who live, host, and create at the highest level.