Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

68 Properties Found. Page 1 of 4

Beautiful Acreage That Could Be Your Very Own "...

Photo of Listing #18039903

$2,288,000 Active

  • 104 Acres

Acreage & Farms

782 Matson Hill 104 Ac Rd, Defiance, MO

MLS® #18039903

Beautiful Acreage That Could Be Your Very Own "stay-cation" Or Close To Home Retreat. Approximately 104+/- Acre Parcel Of Land That Is So Serene And Spectacular That You Will Feel Like You Are On Vacation Every Time You Go. This Property Is Next To Matson H...

90.57 +/- Acres Of Open And Wooded Ground. Acce...

REDUCED 22% Photo of Listing #18007816

$1,766,115 Active

  • 90.57 Acres

Acreage & Farms

S Hwy 94, Defiance, MO

MLS® #18007816

90.57 +/- Acres Of Open And Wooded Ground. Access To The Katy Trail From The South End Of The Property, Some Of This Section Is In The Flood Plain. Located Near Klondike Park, Weldon Spring Conservation Area And Lost Valley Hiking Trails. Close To Several...

This Gorgeous Home Is Located Minutes From Ches...

REDUCED 1% Photo of Listing #19006327

$1,339,000 Active

  • 4 Beds
  • 6 Baths
  • 3 Acres
  • 4,270 ft²

Residential

3 Lauderdale Lane, Defiance, MO

MLS® #19006327

This Gorgeous Home Is Located Minutes From Chesterfield Valley. Serenity Is Provided At This Peaceful Home Site In The Development Of, The Crossings At Lauderdale Estates. The Exterior Of This Home Has A "big Cedar Lodge" Timber Look And Provides An Enterta...

Incredible Opportunity If You’re Looking For Pr...

Photo of Listing #19014661

$1,199,000 Active

  • 4 Beds
  • 6 Baths
  • 30 Acres
  • 4,900 ft²

Residential

150 Homestead Ridge, Defiance, MO

MLS® #19014661

Incredible Opportunity If You’re Looking For Privacy And A Luxury Estate. This Stunning Property Has Over 5900 Sqft Of Living Space, On 30 Acres That Is Complete W/ A 2 Acre Lake, Stable And Pasture And Features Gorgeous Views That Can Only Be Understood By...

The Newest Most Prestigious Development In Defi...

Photo of Listing #19010718

$950,000 Active

  • 3 Beds
  • 3 Baths
  • 3.37 Acres
  • 3,125 ft²

New Construction

9 Blue Sky Drive - Tbb, Defiance, MO

MLS® #19010718

The Newest Most Prestigious Development In Defiance Mo! Kohler Development Is Launching Phase One Of Kohler Estates; Its Newest Luxury Subdivision. Kohler Estates, Located Just Minutes From Shopping, Entertainment, Schools, Recreation, Parks, Golf And Eas...

Beautifully Maintained Home Sitting On A Privat...

NEW Photo of Listing #19017737

$925,000 Active

  • 4 Beds
  • 5 Baths
  • 4.45 Acres
  • 3,889 ft²

Residential

221 Northlind Dr, Defiance, MO

MLS® #19017737

Beautifully Maintained Home Sitting On A Private 4.45 Acre Lot W/woods, Sprinkler, Fabulous L Shaped Salt Water Pool W/pool House, Hot Tub, Paver Patio, Screened In Porch! Impeccably Maintained 35'x35' Detached Garage, Insulated, Drywalled & Painted W/12' A...

The Newest Most Prestigious Development In Defi...

Photo of Listing #19010697

$925,000 Active

  • 3 Beds
  • 3 Baths
  • 3.01 Acres
  • 3,125 ft²

New Construction

1 Redeemer Ct - Tbb, Defiance, MO

MLS® #19010697

The Newest Most Prestigious Development In Defiance Mo! Kohler Development Is Launching Phase One Of Kohler Estates; Its Newest Luxury Subdivision. Kohler Estates, Located Just Minutes From Shopping, Entertainment, Schools, Recreation, Parks, Golf And Eas...

Just Listed! New 4 Bedroom, 4.5 Bath Split Bedr...

Photo of Listing #19002128

$889,500 Active

  • 4 Beds
  • 5 Baths
  • 3.23 Acres
  • 3,099 ft²

Residential

3725 Toedebusch Rd, Defiance, MO

MLS® #19002128

Just Listed! New 4 Bedroom, 4.5 Bath Split Bedroom Ranch Inventory Home By Js Clement Construction Now Under Construction At White Heron Estates. Picturesque 3+ Acre Home Site. Exceptional Quality W/impressive High End Features & Finishes. Brick & Stone Fro...

Welcome To The Yellow Farmhouse Vineyard! Featu...

REDUCED 2% Photo of Listing #18004442

$855,000 Active

  • 7.04 Acres

Commercial & Indr.

100 Defiance Rd Unit 6.84ac, Defiance, MO

MLS® #18004442

Welcome To The Yellow Farmhouse Vineyard! Features 2 Homes, Tasting & Storage Room, Outdoor Pavilion & So Much More. It Sits On The 4 Corners Of Defiance Facing The Missouri River W/gorgeous Views. The Main House Feat 2 Decks, Full Kitchen, Dining/rec Room,...

Traditional Country Style Home With Wrap Around...

REDUCED 12% Photo of Listing #19009504

$730,000 Active

  • 5 Beds
  • 3 Baths
  • 16.02 Acres
  • 3,302 ft²

Residential

3675 Highway D, Defiance, MO

MLS® #19009504

Traditional Country Style Home With Wrap Around Porch And 3 Active Roof Dormers On 16.02+/- Acres . Spacious Kitchen With Custom Cabinets, Breakfast Bar, And Separate Dining Room.the Open Floor Plan Has A Large Family Room With A Gas Fireplace, Hardwood Flo...

Traditional Country Style Home With Wrap Around...

REDUCED 12% Photo of Listing #19008914

$730,000 Active

  • 5 Beds
  • 3 Baths
  • 16.02 Acres
  • 3,302 ft²

Acreage & Farms

3675 Highway D, Defiance, MO

MLS® #19008914

Traditional Country Style Home With Wrap Around Porch And 3 Active Roof Dormers On 16.02+/- Acres . Spacious Kitchen With Custom Cabinets, Breakfast Bar, And Separate Dining Room.the Open Floor Plan Has A Large Family Room With A Gas Fireplace, Hardwood Flo...

Location,location, Location. Attention Buil...

REDUCED 10% Photo of Listing #19016517

$717,000 Active

  • 37.74 Acres

Acreage & Farms

Old Colony Rd, Defiance, MO

MLS® #19016517

Location,location, Location. Attention Builders & Developers – 37.74 Acre Heavily Wooded Parcel On Old Colony Rd Just Off Of Hwy Dd In Defiance – Flanked By The Bush Wildlife Area And The Weldon Springs Wildlife Area. Exactly 10 Minutes From The Interse...

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick ...

Photo of Listing #18084213

$700,000 Active

  • 3 Beds
  • 4 Baths
  • 3.01 Acres
  • 3,398 ft²

Residential

321 Matts Way, Defiance, MO

MLS® #18084213

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick Front Custom-built Ranch Rests Upon A Sprawling 3 Acre Gently Rolling Lot Backing To Woods. The Open Floorplan Greets You W Hardwood Flooring In The Entry & A Soaring Cathedral Ceiling Stretching Rising Above T...

Don't Miss This Beautiful Lake Front Home Sitti...

REDUCED 2% Photo of Listing #18041904

$575,000 Active

  • 3 Beds
  • 3 Baths
  • 6.88 Acres
  • 2,689 ft²

Residential

687 Boone Ridge Trail, Defiance, MO

MLS® #18041904

Don't Miss This Beautiful Lake Front Home Sitting On 6.88 Acres In Saddleback Subdivision. Saddleback Is Well Known For Its Amazing Lake, Amazing Sunrises And Sunsets In The Middle Of Wine Country And So Close To Many Area Parks. This Home Includes: Hardw...

This Impressive, Rambling 1.5 Story Home With W...

Photo of Listing #18057350

$550,000 Active

  • 4 Beds
  • 5 Baths
  • 10 Acres
  • 2,989 ft²

Residential

212 Deep Forest Lane, Defiance, MO

MLS® #18057350

This Impressive, Rambling 1.5 Story Home With Wrap Around Porch Is Snuggled Into The Beautiful Boone Valley Area Situated On 10 Lush Ac With Two Ponds, Woods, Open Ground, Mother Nature & Privacy*as You Enter The Home Large Entry Way Will Draw Your Eyes To ...

Tract 6 In Saddleback Subdivision - Defiance, M...

Photo of Listing #18076686

$506,500 Active

  • 20.26 Acres

Acreage & Farms

4 D Boone Ridge Trail, Defiance, MO

MLS® #18076686

Tract 6 In Saddleback Subdivision - Defiance, Mo - This Lot Is Located In The Beautiful Saddleback Subdivision. The Lot Is Totally Wooded And Private. This Lot Has Access To A 70 Acre Lake And A Dock Will Be Provided For This Lot. This Lot Has A Flat, Woode...

Custom Brick & Stone Ranch W/ Spectacular Views...

NEW Photo of Listing #19016461

$500,000 Active

  • 4 Beds
  • 4 Baths
  • 3 Acres
  • 2,988 ft²

Residential

410 Holden Rd, Defiance, MO

MLS® #19016461

Custom Brick & Stone Ranch W/ Spectacular Views Reminiscent Of Chandler Hill Winery. Passive Solar Energy Design Saves On Energy Cost. Luxury Master Suite W/ Dual Vanity, Elevated Jet Tub, Bidet, & Private Deck Access. Gourmet Kitchen W/ Granite Transformat...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-310-9988 for more information about living in Defiance.

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