Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

72 Properties Found. Page 1 of 4

This Gorgeous Home Is Located Minutes From Ches...

REDUCED 6% Photo of Listing #19006327

$1,265,000 Active

  • 4 Beds
  • 6 Baths
  • 3 Acres
  • 4,270 ft²

Residential

3 Lauderdale Lane, Defiance, MO

MLS® #19006327

This Gorgeous Home Is Located Minutes From Chesterfield Valley. Serenity Is Provided At This Peaceful Home Site In The Development Of, The Crossings At Lauderdale Estates. The Exterior Of This Home Has A "big Cedar Lodge" Timber Look And Provides An Enterta...

For Someone Looking For A Great Recreational Pi...

Photo of Listing #19031858

$1,247,000 Active

  • 86 Acres

Acreage & Farms

N/A, Defiance, MO

MLS® #19031858

For Someone Looking For A Great Recreational Piece Just Minutes From Anything You May Need, This Is The Place For You. Just A Short 15 Minute Drive To Hwy 64 Or Just A Short 10 Minute Drive To New Melle. It Is Also Just Minutes From Many Different Wineries ...

Incredible Opportunity If You’re Looking For Pr...

REDUCED 8% Photo of Listing #19014661

$1,099,000 Active

  • 4 Beds
  • 6 Baths
  • 30 Acres
  • 4,900 ft²

Residential

150 Homestead Ridge, Defiance, MO

MLS® #19014661

Incredible Opportunity If You’re Looking For Privacy And A Luxury Estate. This Stunning Property Has Over 5900 Sqft Of Living Space, On 30 Acres That Is Complete W/ A 2 Acre Lake, Stable And Pasture And Features Gorgeous Views That Can Only Be Understood By...

Amazing Brick/stone 1.5 Story Custom Built In E...

Photo of Listing #19026068

$985,000 Active

  • 6 Beds
  • 5 Baths
  • 3.35 Acres
  • 3,638 ft²

Residential

1144 August Lake Dr, Defiance, MO

MLS® #19026068

Amazing Brick/stone 1.5 Story Custom Built In Elegant August Estates Situated On 3.35 Wooded Acres On Quiet Street. Built In 2017 With Gracious Entry & Iron Clad Front Door Opens To Welcoming Separate Dining Room And Arched Doorways. Hand-scraped Wood Floor...

The Newest Most Prestigious Development In Defi...

Photo of Listing #19010718

$950,000 Active

  • 3 Beds
  • 3 Baths
  • 3.37 Acres
  • 3,125 ft²

New Construction

9 Blue Sky Drive - Tbb, Defiance, MO

MLS® #19010718

The Newest Most Prestigious Development In Defiance Mo! Kohler Development Is Launching Phase One Of Kohler Estates; Its Newest Luxury Subdivision. Kohler Estates, Located Just Minutes From Shopping, Entertainment, Schools, Recreation, Parks, Golf And Eas...

The Newest Most Prestigious Development In Defi...

Photo of Listing #19010697

$925,000 Active

  • 3 Beds
  • 3 Baths
  • 3.01 Acres
  • 3,125 ft²

New Construction

1 Redeemer Ct - Tbb, Defiance, MO

MLS® #19010697

The Newest Most Prestigious Development In Defiance Mo! Kohler Development Is Launching Phase One Of Kohler Estates; Its Newest Luxury Subdivision. Kohler Estates, Located Just Minutes From Shopping, Entertainment, Schools, Recreation, Parks, Golf And Eas...

Amazing Price On This Beautifully Maintained Ho...

REDUCED 3% Photo of Listing #19017737

$900,000 Active

  • 4 Beds
  • 5 Baths
  • 4.45 Acres
  • 3,889 ft²

Residential

221 Northlind Dr, Defiance, MO

MLS® #19017737

Amazing Price On This Beautifully Maintained Home Sitting On A Private 4.45 Acre Lot W/woods, Sprinkler, Fabulous L Shaped Salt Water Pool W/pool House, Hot Tub, Paver Patio, Screened In Porch! Impeccably Maintained 35'x35' Detached Garage, Insulated, Drywa...

New 4 Bedroom, 4.5 Bath Split Bedroom Ranch Inv...

Photo of Listing #19002128

$889,500 Active

  • 4 Beds
  • 5 Baths
  • 3.23 Acres
  • 3,099 ft²

Residential

3725 Toedebusch Rd, Defiance, MO

MLS® #19002128

New 4 Bedroom, 4.5 Bath Split Bedroom Ranch Inventory Home By Js Clement Construction Near Completion At White Heron Estates. Picturesque 3+ Acre Home Site. Exceptional Quality W/impressive High End Features & Finishes. Brick & Stone Front Elevation, Lp Sma...

Welcome To The Yellow Farmhouse Vineyard! Featu...

REDUCED 8% Photo of Listing #18004442

$790,000 Active

  • 7.04 Acres

Commercial & Indr.

100 Defiance Rd Unit 6.84ac, Defiance, MO

MLS® #18004442

Welcome To The Yellow Farmhouse Vineyard! Features 2 Homes, Tasting & Storage Room, Outdoor Pavilion & So Much More. It Sits On The 4 Corners Of Defiance Facing The Missouri River W/gorgeous Views. The Main House Feat 2 Decks, Full Kitchen, Dining/rec Room,...

Location,location, Location. Attention Buil...

REDUCED 10% Photo of Listing #19016517

$717,000 Active

  • 37.74 Acres

Acreage & Farms

Old Colony Rd, Defiance, MO

MLS® #19016517

Location,location, Location. Attention Builders & Developers – 37.74 Acre Heavily Wooded Parcel On Old Colony Rd Just Off Of Hwy Dd In Defiance – Flanked By The Bush Wildlife Area And The Weldon Springs Wildlife Area. Exactly 10 Minutes From The Interse...

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick ...

Photo of Listing #18084213

$700,000 Active

  • 3 Beds
  • 4 Baths
  • 3.01 Acres
  • 3,398 ft²

Residential

321 Matts Way, Defiance, MO

MLS® #18084213

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick Front Custom-built Ranch Rests Upon A Sprawling 3 Acre Gently Rolling Lot Backing To Woods. The Open Floorplan Greets You W Hardwood Flooring In The Entry & A Soaring Cathedral Ceiling Stretching Rising Above T...

“3675 Highway D, Defiance Is Sitting On More Th...

REDUCED 2% Photo of Listing #19008914

$685,000 Active

  • 5 Beds
  • 3 Baths
  • 16.02 Acres
  • 3,302 ft²

Acreage & Farms

3675 Highway D, Defiance, MO

MLS® #19008914

“3675 Highway D, Defiance Is Sitting On More Than 15 Acres Of All Usable Pasture In One Of The Most Prestigious Addresses - Closer To The City Than Any Other Property Currently On The Market Without Restrictions, Covenants, And No Hoa Fees! Zoned Agricultu...

Experience Luxury-living On The Privacy Of Your...

Photo of Listing #19028963

$650,000 Active

  • 4 Beds
  • 4 Baths
  • 3.27 Acres
  • 2,786 ft²

Residential

3916 Indian Ridge Lane, Defiance, MO

MLS® #19028963

Experience Luxury-living On The Privacy Of Your Own 3+ Acre Estate Just Minutes From I-64, Shopping, Dining, And Entertainment Located In The Heart Of Wine Country! Spend Early Mornings Drinking Your Coffee Basking In The Sun From One Of Many Naturally Well...

Spectacular Wooded 3-acre Estate With Privacy, ...

REDUCED 3% Photo of Listing #19027104

$550,000 Active

  • 4 Beds
  • 3 Baths
  • 3.04 Acres
  • 3,032 ft²

Residential

2 Lakeway Ct, Defiance, MO

MLS® #19027104

Spectacular Wooded 3-acre Estate With Privacy, Only 6 Miles From I-64. Stunning Custom Kitchen With Amazing Cabinet Space, Large Island, Granite Counters With Rich Walnut Bar Top, Glass Lighted Display Area, Under-cabinet Lighting, Soft-close Doors, Deep Dr...

“3675 Highway D, Defiance Is Sitting On More Th...

REDUCED 21% Photo of Listing #19009504

$549,900 Active

  • 5 Beds
  • 3 Baths
  • 5 Acres
  • 3,302 ft²

Residential

3675 Highway D, Defiance, MO

MLS® #19009504

“3675 Highway D, Defiance Is Sitting On More Than 15 Acres Of All Usable Pasture In One Of The Most Prestigious Addresses - Closer To The City Than Any Other Property Currently On The Market Without Restrictions, Covenants, And No Hoa Fees! Zoned Agricultu...

Estate Home On 21 Acres! This Is A Multi-level...

Photo of Listing #19030360

$539,500 Active

  • 4 Beds
  • 4 Baths
  • 21 Acres
  • 3,500 ft²

Residential

151 Callaway Ridge Dr, Defiance, MO

MLS® #19030360

Estate Home On 21 Acres! This Is A Multi-level Home With Many Features! The Kitchen Has A Center Island That You Can Cook & Entertain Around Plus Granite Countertops, Plenty Of Cabinets, A Desk Area, & 2 Pantries. Walk Out Onto The Maintenace Free Deck T...

Sensational 3 Bedroom, 2 Full/2 Half Baths, Ran...

NEW Photo of Listing #19036609

$495,000 Active

  • 3 Beds
  • 4 Baths
  • 7.59 Acres
  • 1,970 ft²

Residential

2347 Callaway Fork Rd, Defiance, MO

MLS® #19036609

Sensational 3 Bedroom, 2 Full/2 Half Baths, Ranch Style Home With An Amazing 3600 Sq Ft Of Living Space Including A Partially Finished Lower Level With Dual Walkouts, Bath, Wet Bar & More. Stunning Exterior, An Attached 3 Car Garage, A Detached 3 Car Garag...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-310-9988 for more information about living in Defiance.

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