Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

37 Properties Found. Page 1 of 3

Luxury Estate, With Over 5900 Sqft Of Living Sp...

Photo of Listing #17059579

$1,479,000 Active

  • 4 Beds
  • 6 Baths
  • 43.97 Acres
  • 4,900 ft²

Residential

1098 Highway F, Defiance, MO

MLS® #17059579

Luxury Estate, With Over 5900 Sqft Of Living Space, On Almost 44 Acres That Is Complete With A 2 Acre Lake, Guest Cabin, 2 Stables With Pastures And Road Frontage To Hwy F With Private Driveway. Gorgeous Views That Can Only Be Understood By Seeing Them For...

Beautiful Historic Farm With Highway F Road Fro...

REDUCED 15% Photo of Listing #17009255

$1,373,750 Active

  • 157 Acres

Acreage & Farms

1403 Highway F 157+/- Acres, Defiance, MO

MLS® #17009255

Beautiful Historic Farm With Highway F Road Frontage Near Augusta. Property Suitable For Horses, Cattle, With Cropland, Pasture, And Woods. Femme Osage Creek Running Through Property. Rolling And Hilly Agricultural Land. 157ac

Exquisite Design,elegant Details In The Gorgeou...

Photo of Listing #17054105

$1,290,000 Active

  • 5 Beds
  • 7 Baths
  • 2.86 Acres
  • 3,326 ft²

Residential

220 Northlind Dr, Defiance, MO

MLS® #17054105

Exquisite Design,elegant Details In The Gorgeous Custom Built Estate.the Brick/stone Elevation,stone Walk Over Water Fall, Motor Court With Attached 3 Car Oversized Garage & Detached 52 X 40 *4 Car Two Deep Plus Garage Office With Gas Fp, Full Bath & Worksh...

Luxury Estate, With Over 5900 Sqft Of Living Sp...

REDUCED 19% Photo of Listing #17013352

$1,199,000 Active

  • 4 Beds
  • 6 Baths
  • 33.92 Acres
  • 5,900 ft²

Acreage & Farms

150 Homestead Ridge, Defiance, MO

MLS® #17013352

Luxury Estate, With Over 5900 Sqft Of Living Space, On Almost 34 Acres That Is Complete With A 2 Acre Lake, Guest Cabin, Stable And Pasture. Gorgeous Views That Can Only Be Understood By Seeing Them For Yourself. The Property Provides Complete Privacy , As ...

Luxury Estate, With Over 5900 Sqft Of Living Sp...

REDUCED 19% Photo of Listing #17013238

$1,199,000 Active

  • 4 Beds
  • 6 Baths
  • 33.92 Acres
  • 4,900 ft²

Residential

150 Homestead Ridge, Defiance, MO

MLS® #17013238

Luxury Estate, With Over 5900 Sqft Of Living Space, On Almost 34 Acres That Is Complete With A 2 Acre Lake, Guest Cabin, Stable And Pasture. Gorgeous Views That Can Only Be Understood By Seeing Them For Yourself. The Property Provides Complete Privacy , As ...

New 4,167 Sq Ft 1.5 Story Inventory Home By Js ...

Photo of Listing #17081594

$999,000 Active

  • 4 Beds
  • 4 Baths
  • 3 Acres
  • 4,176 ft²

Residential

5-lot White Heron Estates, Defiance, MO

MLS® #17081594

New 4,167 Sq Ft 1.5 Story Inventory Home By Js Clement Construction Now Under Way At White Heron Estates. Exceptional Quality And Impressive High End Features And Finishes. More Details Coming Soon.

Unbelievable Views Abound From This 50+/- Acres...

Photo of Listing #17052062

$975,000 Active

  • 50 Acres

Acreage & Farms

S Hwy 94, Defiance, MO

MLS® #17052062

Unbelievable Views Abound From This 50+/- Acres Overlooking The Mo River Bottoms And A Peak At St. Albans Bluffs. You Won't Be Able To Wait To Clear Additional Trees And Build Your Dream Home Here. This Parcel Has Been A Part Of The Daniel Boone's History A...

"expect To Be Impressed" This Gorgeous Home Is ...

Photo of Listing #17070637

$895,000 Active

  • 5 Beds
  • 5 Baths
  • 31 Acres
  • 3,852 ft²

Residential

1245 Highway F, Defiance, MO

MLS® #17070637

"expect To Be Impressed" This Gorgeous Home Is In A Private Setting Nestled In The Hills On 31 Acres With Amazing Views From Every Direction. There Is Additional Land Available Too. As You Enter The 2 Story Foyer You Will Feel The Warmth Provided By The Ope...

"expect To Be Impressed" This Gorgeous Home Is ...

Photo of Listing #17070651

$895,000 Active

  • 5 Beds
  • 5 Baths
  • 31 Acres
  • 3,852 ft²

Acreage & Farms

1245 Highway F, Defiance, MO

MLS® #17070651

"expect To Be Impressed" This Gorgeous Home Is In A Private Setting Nestled In The Hills On 31 Acres With Amazing Views From Every Direction And Additional Land Available. As You Enter The 2 Story Foyer You Will Feel The Warmth Provided By The Open Floor Pl...

This Beautiful Kohler Development Home With An ...

NEW Photo of Listing #17081576

$750,000 Active

  • 3 Beds
  • 3 Baths
  • 3.18 Acres
  • 3,125 ft²

Residential

1275 Kohlers Lane, Defiance, MO

MLS® #17081576

This Beautiful Kohler Development Home With An Open Concept Plan Sits Atop 3+ Acres Overlooking A Private Wooded Lot. Home Offers So Many Upgrades Including 10' Ceilings, Crown Molding, Hardwood Floors, Custom Cabinets, Built In Bookshelves, Tray Ceilings, ...

Custom 1.5 Story Home On 3 Acres Offers A Priva...

Photo of Listing #17078507

$749,900 Active

  • 4 Beds
  • 5 Baths
  • 3 Acres
  • 3,628 ft²

Residential

1277 August Estates Dr, Defiance, MO

MLS® #17078507

Custom 1.5 Story Home On 3 Acres Offers A Private Getaway Yet Great Access! Chef's Kitchen With Hearth Room/stone Fireplace, Breakfast Bar, Spacious Breakfast Room, Stainless Appliances,and Glazed Maple Cabinets! Spacious Main Floor Master Suite Includes U...

Truly Spectacular Custom Ranch With Upgrades & ...

Photo of Listing #17042358

$700,000 Active

  • 4 Beds
  • 4 Baths
  • 2.94 Acres

Residential

321 Matts Way, Defiance, MO

MLS® #17042358

Truly Spectacular Custom Ranch With Upgrades & Amenities Above & Beyond Your Expectations. 3398 Sq.ft. On Main Floor. Huge Vaulted Great Room W/wall Of Windows, Gas Fireplace, Built-in Shelves, Gorgeous Cherry Wet Bar. Fabulous Kitchen Features Upgraded App...

Architect Lauren Stratman Showcases This Except...

REDUCED 3% Photo of Listing #17028674

$679,900 Active

  • 4 Beds
  • 5 Baths
  • 3.02 Acres
  • 4,228 ft²

Residential

734 Crown Pointe Farms Dr, Defiance, MO

MLS® #17028674

Architect Lauren Stratman Showcases This Exception 1.5 Story Home Nested On 3 Acres In A Premier Subdivision In Beautiful Definace. This Estate Style Home Of Brick & Stone Elevation & Grand Solid Wood Entry Door Sets The Pace For You To Enjoy The Luxurious ...

Motivated Seller; Make Offer~atrium Ranch On 3....

REDUCED 2% Photo of Listing #17074148

$525,000 Active

  • 4 Beds
  • 4 Baths
  • 3.61 Acres
  • 2,670 ft²

Residential

3680 Forest Edge Dr, Defiance, MO

MLS® #17074148

Motivated Seller; Make Offer~atrium Ranch On 3.6 Private Acres W/inground Salt Water Pool & Lake Access! 4 Br's, 4+ Baths, 3car Garage & Detached Heat/cool 26x22 Garage. Greatrm W/vaulted Ceilings, Woodburnfp W/insert/blower. Striking Atrium Windows Overloo...

This One Of A Kind, 19.27+/- Acres, In The Hear...

Photo of Listing #17068288

$479,823 Active

  • 19.27 Acres

Acreage & Farms

Old Colony, Defiance, MO

MLS® #17068288

This One Of A Kind, 19.27+/- Acres, In The Heart Of Defiance, Offers So Much For Your Enjoyment. Starting With Your Very Own Fishing Lake To The Open Land To House Livestock To The Wooded Land For The Ultimate Privacy. The Property Also Offers Some Flat To ...

Attention Builders! Possible Division Would ...

Photo of Listing #17072446

$449,000 Active

  • 51.29 Acres

Residential Lots

14-lots Udall Ct., Defiance, MO

MLS® #17072446

Attention Builders! Possible Division Would Make 14 3acre Lots. Desirable Large Wooded Parcel Of 51 +- Acres In St. Charles County Has Open Slate Of Possibilities. Would Make For An Excellent Development Parcel. Engineering And Soil Tests For 3 Acre Lots...

Attention Builders! Possible Division Would ...

Photo of Listing #17070838

$449,000 Active

  • 51.29 Acres

Acreage & Farms

51-acres Udall Ct., Defiance, MO

MLS® #17070838

Attention Builders! Possible Division Would Make 14 3acre Lots. Desirable Large Wooded Parcel Of 51 +- Acres In St. Charles County Has Open Slate Of Possibilities. Would Make For An Excellent Development Parcel. Engineering And Soil Tests For 3 Acre Lots...

Custom Built Two Story Home On Wooded 3 Acre Lo...

Photo of Listing #17074142

$405,000 Active

  • 3 Beds
  • 3 Baths
  • 3 Acres
  • 2,396 ft²

Residential

196 Timber Pines Dr, Defiance, MO

MLS® #17074142

Custom Built Two Story Home On Wooded 3 Acre Lot In A Beautiful Subdivision Near Missouri Wineries! This Home Features A New Roof, New Carpeting 9/2017, Oversized 2 Car Attached Garage Plus A 30x30 Detached Garage With A Full Loft! Quaint Front Porch Leads ...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-282-8282 for more information about living in Defiance.

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