Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

36 Properties Found. Page 1 of 2

Beautiful Historic Farm With Highway F Road Fro...

REDUCED 15% Photo of Listing #17009255

$1,373,750 Active

  • 157 Acres

Acreage & Farms

1403 Highway F 157+/- Acres, Defiance, MO

MLS® #17009255

Beautiful Historic Farm With Highway F Road Frontage Near Augusta. Property Suitable For Horses, Cattle, With Cropland, Pasture, And Woods. Femme Osage Creek Running Through Property. Rolling And Hilly Agricultural Land. 157ac

Exquisite Design,elegant Details In The Gorgeou...

Photo of Listing #17054105

$1,290,000 Active

  • 5 Beds
  • 7 Baths
  • 2.86 Acres
  • 3,326 ft²

Residential

220 Northlind Dr, Defiance, MO

MLS® #17054105

Exquisite Design,elegant Details In The Gorgeous Custom Built Estate.the Brick/stone Elevation,stone Walk Over Water Fall, Motor Court With Attached 3 Car Oversized Garage & Detached 52 X 40 *4 Car Two Deep Plus Garage Office With Gas Fp, Full Bath & Worksh...

New 4,167 Sq Ft 1.5 Story Inventory Home By Js ...

Photo of Listing #17081594

$999,000 Active

  • 4 Beds
  • 4 Baths
  • 3 Acres
  • 4,176 ft²

Residential

5-lot White Heron Estates, Defiance, MO

MLS® #17081594

New 4,167 Sq Ft 1.5 Story Inventory Home By Js Clement Construction Under Way At White Heron Estates. Exceptional Quality And Impressive High End Features And Finishes. Full Brick & Stone Front Elevation, James Hardie Siding, Pella Windows, Custom Iron Entr...

Unbelievable Views Abound From This 50+/- Acres...

Photo of Listing #17052062

$975,000 Active

  • 50 Acres

Acreage & Farms

S Hwy 94, Defiance, MO

MLS® #17052062

Unbelievable Views Abound From This 50+/- Acres Overlooking The Mo River Bottoms And A Peak At St. Albans Bluffs. You Won't Be Able To Wait To Clear Additional Trees And Build Your Dream Home Here. This Parcel Has Been A Part Of The Daniel Boone's History A...

This Beautiful Kohler Development Home With An ...

Photo of Listing #17081576

$750,000 Active

  • 3 Beds
  • 3 Baths
  • 3.18 Acres
  • 3,125 ft²

Residential

1275 Kohlers Lane, Defiance, MO

MLS® #17081576

This Beautiful Kohler Development Home With An Open Concept Plan Sits Atop 3+ Acres Overlooking A Private Wooded Lot. Home Offers So Many Upgrades Including 10' Ceilings, Crown Molding, Hardwood Floors, Custom Cabinets, Built In Bookshelves, Tray Ceilings, ...

Custom 1.5 Story Home On 3 Acres Offers A Priva...

Photo of Listing #17078507

$749,900 Active

  • 4 Beds
  • 5 Baths
  • 3 Acres
  • 3,628 ft²

Residential

1277 August Estates Dr, Defiance, MO

MLS® #17078507

Custom 1.5 Story Home On 3 Acres Offers A Private Getaway Yet Great Access! Chef's Kitchen With Hearth Room/stone Fireplace, Breakfast Bar, Spacious Breakfast Room, Stainless Appliances,and Glazed Maple Cabinets! Spacious Main Floor Master Suite Includes U...

Own This One Of A Kind Absolute Gem Of An Estat...

REDUCED 4% Photo of Listing #17009064

$675,000 Active

  • 4 Beds
  • 3 Baths
  • 8.18 Acres
  • 3,049 ft²

Residential

1481 Highway F, Defiance, MO

MLS® #17009064

Own This One Of A Kind Absolute Gem Of An Estate Located Just A Mile Or So From Chandler Hill Winery And Near The Historic Daniel Boone Home. This Amazing Country Estate Hosts A Truly Custom Home With Lots And Lots Of Windows From Which To Soak In The Amaz...

Stunning Custom 1.5 Story Show Stopper! Home Si...

Photo of Listing #17093290

$549,900 Active

  • 3 Beds
  • 3 Baths
  • 5.06 Acres
  • 2,900 ft²

Residential

9 Callaway Ridge Ct, Defiance, MO

MLS® #17093290

Stunning Custom 1.5 Story Show Stopper! Home Sits On 5 Acres, 3 Car Garage, Walk-out Ll & More Upgrades Than You Can Imagine! Mflr Features 9ft Ceilings(lr Has Soaring 18ft Ceilings), Tobacco Stained Wide-plank Hardwood Floors, Cobblestone Wood-burning Fire...

Open House 12/17 1-3 Motivated Seller; Make Off...

REDUCED 1% Photo of Listing #17074148

$519,900 Active

  • 4 Beds
  • 4 Baths
  • 3.61 Acres
  • 3,102 ft²

Residential

3680 Forest Edge Dr, Defiance, MO

MLS® #17074148

Open House 12/17 1-3 Motivated Seller; Make Offer~atrium Ranch On 3.6 Private Acres W/inground Salt Water Pool & Lake Access! 4 Br's, 4+ Baths, 3car Garage & Detached Heat/cool 26x22 Garage. Greatrm W/vaulted Ceilings, Woodburnfp W/insert/blower. Striking A...

This One Of A Kind, 19.27+/- Acres, In The Hear...

REDUCED 6% Photo of Listing #17068288

$449,900 Active

  • 19.27 Acres

Acreage & Farms

Old Colony, Defiance, MO

MLS® #17068288

This One Of A Kind, 19.27+/- Acres, In The Heart Of Defiance, Offers So Much For Your Enjoyment. Starting With Your Very Own Fishing Lake To The Open Land To House Livestock To The Wooded Land For The Ultimate Privacy. The Property Also Offers Some Flat To ...

Attention Builders! Possible Division Would ...

Photo of Listing #17072446

$449,000 Active

  • 51.29 Acres

Residential Lots

14-lots Udall Ct., Defiance, MO

MLS® #17072446

Attention Builders! Possible Division Would Make 14 3acre Lots. Desirable Large Wooded Parcel Of 51 +- Acres In St. Charles County Has Open Slate Of Possibilities. Would Make For An Excellent Development Parcel. Engineering And Soil Tests For 3 Acre Lots...

Attention Builders! Possible Division Would ...

Photo of Listing #17070838

$449,000 Active

  • 51.29 Acres

Acreage & Farms

51-acres Udall Ct., Defiance, MO

MLS® #17070838

Attention Builders! Possible Division Would Make 14 3acre Lots. Desirable Large Wooded Parcel Of 51 +- Acres In St. Charles County Has Open Slate Of Possibilities. Would Make For An Excellent Development Parcel. Engineering And Soil Tests For 3 Acre Lots...

Custom Built Two Story Home On Wooded 3 Acre Lo...

REDUCED 1% Photo of Listing #17074142

$399,900 Active

  • 3 Beds
  • 3 Baths
  • 3 Acres
  • 2,396 ft²

Residential

196 Timber Pines Dr, Defiance, MO

MLS® #17074142

Custom Built Two Story Home On Wooded 3 Acre Lot In A Beautiful Subdivision Near Missouri Wineries! This Home Features A New Roof, New Carpeting 9/2017, Oversized 2 Car Attached Garage Plus A 30x30 Detached Garage With A Full Loft! Quaint Front Porch Leads ...

A Touch Of Heaven! This Beautiful Home Is Nestl...

REDUCED 3% Photo of Listing #17085693

$389,000 Active

  • 5 Beds
  • 3 Baths
  • 5.07 Acres
  • 2,825 ft²

Residential

285 Callaway Ridge, Defiance, MO

MLS® #17085693

A Touch Of Heaven! This Beautiful Home Is Nestled On 5 Acres With A Majestic View! Tree Lined With A Creek Across The Back, Split Rail Fence Adds To The Welcoming Charm. Subdivision Has 160 Acre Lake For Your Boating Pleasure, Swim Area, Boat Ramp And Dock,...

Amazing Atrium Ranch On 5.6 Ac Located In The B...

Photo of Listing #17091729

$375,000 Active

  • 4 Beds
  • 3 Baths
  • 6.67 Acres
  • 3,017 ft²

Residential

50 White River Lane, Defiance, MO

MLS® #17091729

Amazing Atrium Ranch On 5.6 Ac Located In The Beautiful 160 Ac Lake Community Of Callaway Valley Estates. This One Owner Custom Home Has Tons Of Space. From The Entry View The Huge Great Room With Soaring Vault, Gas Fireplace, Tons Of Windows Overlooking Th...

Spacious Log Home On 9 Acres!! This Gorgeous P...

Photo of Listing #17086211

$375,000 Active

  • 4 Beds
  • 3 Baths
  • 9 Acres
  • 2,206 ft²

Residential

2533 Hwy F, Defiance, MO

MLS® #17086211

Spacious Log Home On 9 Acres!! This Gorgeous Property Has So Much To Offer. Enjoy The Privacy And Serenity Of The Beautiful Surroundings. The Spacious Log Home Features A Large Eat-in Kitchen With Separate Dining Room Complete With Double Doors. The New...

Charming Log Home Nestled On 3.36 Wooded Acres ...

Photo of Listing #17072118

$349,900 Active

  • 3 Beds
  • 4 Baths
  • 3.17 Acres
  • 2,557 ft²

Residential

8 Whippoorwill, Defiance, MO

MLS® #17072118

Charming Log Home Nestled On 3.36 Wooded Acres On The Outskirts Of New Melle In Centennial Farms! Lovely Setting With Large Front Porch And Winding Stone Pathway Welcomes You This Tranquil Haven In The Woods. Great Room Complete With Floor To Ceiling Woodbu...

This Waterfront Lot, Approx 1200' Of Shoreline,...

REDUCED 12% Photo of Listing #16057456

$349,500 Active

  • 6.95 Acres

Residential Lots

5-lot Boone Ridge Trail, Defiance, MO

MLS® #16057456

This Waterfront Lot, Approx 1200' Of Shoreline, Has Amazing Views And Several Different Building Sites For Your Dream Home. While Selecting Your Building Site You Can Use The Existing Custom-built Weather Shelter To Enjoy Fishing, Swimming, Boating, Or Rela...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-282-8282 for more information about living in Defiance.

Information from Third Parties, Deemed Reliable but Not Verified.
Listings displaying the MARIS logo are courtesy of Mid America Regional Information Systems Internet Data Exchange.