Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

42 Properties Found. Page 1 of 3

Opportunities Like This Are Rare To Come By. Th...

REDUCED 2% Photo of Listing #19034275

$1,349,000 Active

  • 5 Beds
  • 7 Baths
  • 3 Acres
  • 3,326 ft²

Residential

220 Northlind Dr, Defiance, MO

MLS® #19034275

Opportunities Like This Are Rare To Come By. This Magnificent, 13-yr Old Custom Built Estate, On A Scenic 2.86 Acre Private Lot Is Only 15 Min From Chesterfield. The Long Driveway, The Expansive Lawn, The Common Ground W/deer & Woods. Pull Up To The Courty...

This Gorgeous Home Is Located Minutes From Ches...

REDUCED 6% Photo of Listing #19006327

$1,265,000 Active

  • 4 Beds
  • 6 Baths
  • 3 Acres
  • 2,757 ft²

Residential

3 Lauderdale Lane, Defiance, MO

MLS® #19006327

This Gorgeous Home Is Located Minutes From Chesterfield Valley. Serenity Is Provided At This Peaceful Home Site In The Development Of, The Crossings At Lauderdale Estates. The Exterior Of This Home Has A "big Cedar Lodge" Timber Look And Provides An Enterta...

For Someone Looking For A Great Recreational Pi...

Photo of Listing #19031858

$1,247,000 Active

  • 86 Acres

Acreage & Farms

N/A, Defiance, MO

MLS® #19031858

For Someone Looking For A Great Recreational Piece Just Minutes From Anything You May Need, This Is The Place For You. Just A Short 15 Minute Drive To Hwy 64 Or Just A Short 10 Minute Drive To New Melle. It Is Also Just Minutes From Many Different Wineries ...

Incredible Opportunity If You’re Looking For Pr...

Photo of Listing #19045111

$1,199,000 Active

  • 4 Beds
  • 6 Baths
  • 34 Acres
  • 4,900 ft²

Residential

150 Homestead Ridge, Defiance, MO

MLS® #19045111

Incredible Opportunity If You’re Looking For Privacy & A Luxury Estate W/ 2 Properties. The Primary Residence Has Over 5900 Sq/ft Of Living Space, 34 Acres Complete W/ A 2 Acre Lake, Stable & Pastures Along W/ Gorgeous Views That Can Only Be Understood By S...

Amazing Price On This Beautifully Maintained Ho...

REDUCED 3% Photo of Listing #19017737

$900,000 Active

  • 4 Beds
  • 5 Baths
  • 4.45 Acres
  • 3,889 ft²

Residential

221 Northlind Dr, Defiance, MO

MLS® #19017737

Amazing Price On This Beautifully Maintained Home Sitting On A Private 4.45 Acre Lot W/woods, Sprinkler, Fabulous L Shaped Salt Water Pool W/pool House, Hot Tub, Paver Patio, Screened In Porch! Impeccably Maintained 35'x35' Detached Garage, Insulated, Drywa...

Stunning 1.5 Story Brick/stone House On A Priv ...

Photo of Listing #19041078

$850,000 Active

  • 4 Beds
  • 5 Baths
  • 3 Acres
  • 4,784 ft²

Residential

1277 August Estates Dr, Defiance, MO

MLS® #19041078

Stunning 1.5 Story Brick/stone House On A Priv 3acre Wooded Lot.fully Remodeled Home W/custom Designed Kitchen W/expansive 10’quartz Island And Butlers Bar W/bev Fridge, Creating Perfect Space For Hosting Family/friends.finishes Include 42” Custom Inset Cab...

Only 13.6 Miles To Hwy 94/i64! 14.9 Miles To Hw...

Photo of Listing #19043730

$825,000 Active

  • 4 Beds
  • 4 Baths
  • 6.61 Acres
  • 3,773 ft²

Residential

19 Horn Cove Lane, Defiance, MO

MLS® #19043730

Only 13.6 Miles To Hwy 94/i64! 14.9 Miles To Hwy Z/i70! Custom Built! 1.5 Story! 6.61 Wooded Acres! Private 70 Acre Sub Lake W/a Private Dock! Newer Swim Spa! 22 X 20 Patio! Fire Pit! Brand New 300+ Sq Ft Deck! 36x28 3 Car Detached Garage W/an Attached 2 Ca...

37.74 Heavily Wooded Acres Just Off Of Hwy Dd I...

Photo of Listing #19016517

$717,000 Active

  • 37.74 Acres

Acreage & Farms

Old Colony Rd, Defiance, MO

MLS® #19016517

37.74 Heavily Wooded Acres Just Off Of Hwy Dd In Defiance. Near The Bush Wildlife Area, The Weldon Springs Wildlife Area, And Wine Country Exactly 10 Minutes From Hwy 40 & 94. City Water, Electric, Phone And High Speed Internet To The Site. Possible Small D...

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick ...

Photo of Listing #18084213

$700,000 Active

  • 3 Beds
  • 4 Baths
  • 3.01 Acres
  • 3,398 ft²

Residential

321 Matts Way, Defiance, MO

MLS® #18084213

Simply Amazing! This Huge 3 Bed/3.5 Bath Brick Front Custom-built Ranch Rests Upon A Sprawling 3 Acre Gently Rolling Lot Backing To Woods. The Open Floorplan Greets You W Hardwood Flooring In The Entry & A Soaring Cathedral Ceiling Stretching Rising Above T...

The Combination Of Location, Acreage, Home Size...

REDUCED 2% Photo of Listing #19009504

$614,900 Active

  • 5 Beds
  • 3 Baths
  • 16 Acres
  • 3,302 ft²

Residential

3675 Highway D, Defiance, MO

MLS® #19009504

The Combination Of Location, Acreage, Home Size,and Price Make 3675 Highway D A Treasure. 16 Acre Estate Closer To The City Than Any Similar Property–no Covenants Or Hoa Fees! With This Large 5 Br, 2.5 Ba Home (full Bath Stubbed In Basement) Reduced In Pric...

The Combination Of Location, Acreage, Home Size...

REDUCED 2% Photo of Listing #19008914

$614,900 Active

  • 5 Beds
  • 3 Baths
  • 16 Acres
  • 3,302 ft²

Acreage & Farms

3675 Highway D, Defiance, MO

MLS® #19008914

The Combination Of Location, Acreage, Home Size, And Price Make 3675 Highway D A Treasure. 16 Acre Estate Closer To The City Than Any Similar Property–no Covenants Or Hoa Fees! With This Large 5 Br, 2.5 Ba Home (full Bath Stubbed In Basement) Reduced In Pri...

6.99 Acres Total Including 3 Homes On Property ...

Photo of Listing #19048251

$599,000 Active

  • 6.99 Acres

Commercial & Indr.

100-- 140 Defiance Rd, Defiance, MO

MLS® #19048251

6.99 Acres Total Including 3 Homes On Property Plus Out Buildings. The Corner Of The Property Is Zoned Commercial C-2, Remainder Of The Property Is Agricultural And Residential. 2.5 Acres In Norton Grapes. 100 Seat Pavilion With Stone Fireplace, Stage Lig...

Beautifully Designed Atrium Ranch Home On 3.5 ...

REDUCED 4% Photo of Listing #19039187

$560,000 Active

  • 4 Beds
  • 4 Baths
  • 3.45 Acres
  • 2,604 ft²

Residential

3816 Rooster Ridge Ln, Defiance, MO

MLS® #19039187

Beautifully Designed Atrium Ranch Home On 3.5 Private Acres, Features A Geothermal Heating & Cooling System. 4600 Square Foot, Open Floor Plan W/ First-floor Master Suite, Large His/her Closets, Laundry Room. The Great Room With Gas Fireplace Overlooks A...

Great New Price On This Estate Home With 21 Acr...

REDUCED 3% Photo of Listing #19030360

$524,500 Active

  • 4 Beds
  • 4 Baths
  • 21 Acres
  • 3,500 ft²

Residential

151 Callaway Ridge Dr, Defiance, MO

MLS® #19030360

Great New Price On This Estate Home With 21 Acres! This Is A Multi-level Home With Many Features! The Kitchen Has A Center Island That You Can Cook & Entertain Around Plus Granite Countertops, Plenty Of Cabinets, A Desk Area, & 2 Pantries. Walk Out Onto ...

Sensational 3 Bedroom, 2 Full/2 Half Baths, Ran...

REDUCED 2% Photo of Listing #19036609

$485,000 Active

  • 3 Beds
  • 4 Baths
  • 7.59 Acres
  • 1,970 ft²

Residential

2347 Callaway Fork Rd, Defiance, MO

MLS® #19036609

Sensational 3 Bedroom, 2 Full/2 Half Baths, Ranch Style Home With An Amazing 3600 Sq Ft Of Living Space Including A Partially Finished Lower Level With Dual Walkouts, Bath, Wet Bar & More. Stunning Exterior, An Attached 3 Car Garage, A Detached 3 Car Garag...

Beautiful Ready To Move In Custom Built 1-1/2 S...

REDUCED 2% Photo of Listing #19049582

$459,000 Active

  • 4 Beds
  • 4 Baths
  • 3.59 Acres
  • 2,131 ft²

Residential

3667 Backwoods Hill Ct, Defiance, MO

MLS® #19049582

Beautiful Ready To Move In Custom Built 1-1/2 Story Home On 3.59 Acre Lot On Culdesac Backing To Woods. Brick And Vinyl Exterior, Three Car Oversized Garage, Two Story Entry Way With Eighteen Foot Ceilings And Wood Burning See Through Fire Place In Spacio...

Welcome To This Beautiful 2 Story In Sought Aft...

REDUCED 3% Photo of Listing #19027050

$450,000 Active

  • 4 Beds
  • 4 Baths
  • 5.01 Acres
  • 3,126 ft²

Residential

8 Gastons Trail Ct, Defiance, MO

MLS® #19027050

Welcome To This Beautiful 2 Story In Sought After Callaway Valley On 5 Acres! This 4 Bed, 3 ½ Bath Home With 3 Car Oversized Garage Offers 3,636 Sqft Of Total Living Area To Entertain Your Guests. The Main Floor Features An Open Plan With Tons Of Windows Wi...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-310-9988 for more information about living in Defiance.

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