Defiance Missouri Real Estate

Defiance is a small town located just about 40 miles West of St Louis.  It has been dubbed the “The Gateway to Missouri Wine Country“, and with good reason as the region is known for having some of the best vineyards in the Midwest.   See all the current Defiance MLS listings below, or read more about living in Defiance.  If you'd rather you can also search by map.

Homes For Sale in Defiance, MO

45 Properties Found. Page 1 of 3

Spectacular Residence In The "heart Of Wine Cou...

Photo of Listing #20009921

$2,350,000 Active

  • 8 Beds
  • 7 Baths
  • 69.67 Acres
  • 16,626 ft²

Residential

875 Matson Hill Road, Defiance, MO

MLS® #20009921

Spectacular Residence In The "heart Of Wine Country," With Stunning Views Of 69+ Acres, Rolling Hills, A Sparkling Lake, & An 1850's Cabin! Breathtaking Vistas Make This 15,000+sq. Ft. Prairie Style Home An Ideal Retreat. Built In 2001, This Home Has An Ope...

For Someone Looking For A Great Recreational Pi...

Photo of Listing #19031858

$1,247,000 Active

  • 86 Acres

Farm

Callaway Fork, Defiance, MO

MLS® #19031858

For Someone Looking For A Great Recreational Piece Just Minutes From Anything You May Need, This Is The Place For You. Just A Short 15 Minute Drive To Hwy 64 Or Just A Short 10 Minute Drive To New Melle. It Is Also Just Minutes From Many Different Wineries ...

Freshly Painted & Beautifully Maintained Home O...

Photo of Listing #20013541

$949,500 Active

  • 4 Beds
  • Baths
  • 4.45 Acres
  • 5,647 ft²

Residential

221 Northlind Drive, Defiance, MO

MLS® #20013541

Freshly Painted & Beautifully Maintained Home On 4.45 Acre Lot W/woods, Sprinkler, Fabulous L Shaped Salt Water Pool, Pool House, Hot Tub, Paver Patio, Screened In Porch! Impeccably Maintained 35'x35' Detached Garage,insulated,drywalled & Painted W/12' & 10...

Stunning, Open Custom Built 4 Bdr+ Ranch Home. ...

Photo of Listing #20013151

$699,000 Active

  • 5 Beds
  • Baths
  • 3 Acres
  • 4,150 ft²

Residential

42 Hidden Vista, Defiance, MO

MLS® #20013151

Stunning, Open Custom Built 4 Bdr+ Ranch Home. 3 Acres, Nestled In Trees. Step Into The Foyer W/ Soaring Ceiling & Moldings. Arched Openings On Elegant Dr. Kit. Offers Custom Cabinets, New Ovens, Butler Pantry, Granite & Ct Backsplash, Island Seating. Open ...

Motivated Seller! Duplicate Listing Of Mls# 190...

Photo of Listing #19056866

$689,900 Active

  • 1.45 Acres

Commercial Sale

125 Defiance Road, Defiance, MO

MLS® #19056866

Motivated Seller! Duplicate Listing Of Mls# 19055297. Turnkey Business Opportunity With 4 Large King Suites! Former Inn At Defiance, Renovated In 2019, Near Wineries & Katy Trail. Stone 2-sided Fireplace & Open Entertaining Area. Large Wraparound Porch & Co...

Motivated Seller And Huge Price Drop! Estate Ho...

REDUCED 6% Photo of Listing #19055297

$650,000 Active

  • 4 Beds
  • Baths
  • 1.45 Acres
  • 5,100 ft²

Residential

125 Defiance Road, Defiance, MO

MLS® #19055297

Motivated Seller And Huge Price Drop! Estate Home On 1.5 Acres In The Heart Of Missouri Wine Country. Complete Professional Renovation In 2019. 1st Floor Has 1/2 Bath, Laundry & 3 New Bedroom Suites, 2 With Fireplaces & All With Spa-like Bathrooms. All New ...

3.45 Acres Of Beautiful Trees, Woods & Nature L...

Photo of Listing #20016175

$535,000 Active

  • 4 Beds
  • Baths
  • 3.45 Acres
  • 4,618 ft²

Residential

3816 Rooster Ridge Lane, Defiance, MO

MLS® #20016175

3.45 Acres Of Beautiful Trees, Woods & Nature Life. Gorgeous View From Every Window. Outstanding Floorplan Plus A Large Oversized 3 Car Garage (with Dog Bath). Enjoy Quiet Evenings Having Dinner In The Screened In Porch. Watch Wildlife From Your Lg Deck - G...

Simply Amazing! Nestled Upon A Sprawling 3 Acre...

Photo of Listing #19088860

$509,900 Active

  • 5 Beds
  • 3 Baths
  • 3 Acres
  • 4,000 ft²

Residential

524 Rooster Ridge Court, Defiance, MO

MLS® #19088860

Simply Amazing! Nestled Upon A Sprawling 3 Acre Lot, This Expansive 5 Bed/3 Bath Brick-front Atrium Ranch Features A Cathedral Ceiling Stretching Above The Great Room Where You'll Marvel At The Custom Marble Medallion Inlay At The Entry, A Toasty Fireplace ...

This Stunning Atrium Ranch Sits On A Gorgeous L...

Photo of Listing #20017726

$459,900 Active

  • 4 Beds
  • 3 Baths
  • 3.17 Acres
  • 2,999 ft²

Residential

532 Rooster Ridge Court, Defiance, MO

MLS® #20017726

This Stunning Atrium Ranch Sits On A Gorgeous Lot, Surrounded By Trees & Located On A Cul-de-sac! Step Inside To See The Fabulous Open Floor Plan, With An Amazing View Of Trees & Wildlife Through The Atrium! The Sunroom, Screened Porch & Wrap Around Compo...

5bed/3full,2half Bath 1.5 Story Home Located On...

REDUCED 5% Photo of Listing #19083870

$450,000 Active

  • 5 Beds
  • 4 Baths
  • 3.02 Acres
  • 4,611 ft²

Residential

1354 Lake Hollow Drive, Defiance, MO

MLS® #19083870

5bed/3full,2half Bath 1.5 Story Home Located On A Stunning 3.02 Acres That Backs To Trees. Cozy Lr Boasts Crown Molding, Chair Rail W/wainscoting, Pass Thru Brick Gas Fireplace, Built-in Bookshelves & Dual Sliding Doors That Open To A Large Sunroom & Access...

Have You Been Looking For The Perfect Place For...

NEW Photo of Listing #20019925

$425,000 Active

  • 21.73 Acres
  • 1,066 ft²

Farm

35 Neal Lane, Defiance, MO

MLS® #20019925

Have You Been Looking For The Perfect Place For A Small Winery, Micro-distillery, Micro-brewery Or A Wedding Venue? This Is It! Already Zoned For Agri-tourism, This Property Has The Location, Blacktop Hwy 94 Access In The Heart Of Defiance, The Views And ...

Take A Journey To The Old West! Don't Miss This...

Photo of Listing #20015620

$359,000 Active

  • 4 Beds
  • 3 Baths
  • 3.15 Acres
  • 1,722 ft²

Residential

34 Wilderness Lane, Defiance, MO

MLS® #20015620

Take A Journey To The Old West! Don't Miss This Terrific Ranch With A Western Flair Overlooking 3+ Lush Acres Nestled On A Private Lot On Wilderness Lane. The Great Room Has A Warm, Casual Feeling With Open Spaces Complemented By The Cathedral Ceiling, S...

Tract 6 In Saddleback Subdivision - Defiance, M...

Photo of Listing #19019825

$249,750 Active

  • 9.99 Acres

Land

6 Aj Boone Ridge Trail, Defiance, MO

MLS® #19019825

Tract 6 In Saddleback Subdivision - Defiance, Mo - This Lot Is Located In The Beautiful Saddleback Subdivision. The Lot Is Totally Wooded And Private. This Lot Has Access To A 70 Acre Lake And A Dock Will Be Provided For This Lot. This Lot Has A Flat, Woode...

9 Wooded Acres In Defiance, 1/4 Mile South Of R...

Photo of Listing #20005116

$238,095 Active

  • 9 Acres

Land

Old Colony 9ac Road, Defiance, MO

MLS® #20005116

9 Wooded Acres In Defiance, 1/4 Mile South Of Rooster Ridge Lane On Old Colony Rd. City Water, Electric And Phone/internet To The Site. Not In A Subdivision, No Restrictions And A Nice Lake Site. Great View Private

9 Wooded Acres In Defiance, 1/4 Mile South Of R...

Photo of Listing #20005119

$238,095 Active

  • 9 Acres

Farm

Old Colony 9ac Road, Defiance, MO

MLS® #20005119

9 Wooded Acres In Defiance, 1/4 Mile South Of Rooster Ridge Lane On Old Colony Road. City Water, Electric And Phone/internet To The Site. Not In A Subdivision, No Restrictions And A Nice Lake Site.

Js Clement Construction Is Now Offering 3 Plus ...

Photo of Listing #19086451

$235,000 Active

  • 4.24 Acres

Land

Auden Prairie, Defiance, MO

MLS® #19086451

Js Clement Construction Is Now Offering 3 Plus Acre Home Sites At Their New Residential Development Auden Prairie In St. Charles County. Outstanding Location Off Wilson Rd Near The Intersection Of Hwy D And Dd Between Defiance And Lake St. Louis. Auden Prai...

Build Your Dream Home On This Private, Wooded, ...

Photo of Listing #20016527

$229,900 Active

  • 5 Acres

Land

1 Boone Ridge Trail, Defiance, MO

MLS® #20016527

Build Your Dream Home On This Private, Wooded, Waterfront 5 Acre Lot In The Middle Of Scenic Missouri Wine Country. Saddleback Is A Clear, Stream Fed, 70 Acre Private Lake Stocked With Muskies , Large And Small Mouth Bass And Crappie.. Excellent Location C...

Js Clement Construction Is Now Offering 3 Plus ...

Photo of Listing #19086707

$225,000 Active

  • 4.74 Acres

Land

Auden Prairie, Defiance, MO

MLS® #19086707

Js Clement Construction Is Now Offering 3 Plus Acre Home Sites At Their New Residential Development Auden Prairie In St. Charles County. Outstanding Location Off Wilson Rd Near The Intersection Of Hwy D And Dd Between Defiance And Lake St. Louis. Auden Prai...


Living in Defiance, MO

There are various places of importance in close proximity to Defiance; they are the Yellow Farmhouse Vineyard and Winery, Historic Daniel Boone Home and Boonesfield Village, and Frisella Nursery. Many people travel to this area to visit the historic site of Daniel Boone’s home.  This old home was constructed in the early 1800’s and has thick limestone walls. Listed as a home on the National Register of Historic Places, this extraordinary site is often frequented by those new to the area.  Today, this village is owned and run by the Lindenwood University.  It is one of the great sites that depict life in this time period and give a glimpse into the American frontier experience.

History of Defiance

Around the turn of the century, the little town of Defiance, MO was formed. This area had no name but big plans, as the Katy Railroad began installing a rail system through this region. The unnamed town needed a title with its progress and plans for further development.  Town officials wanted to use the name Parsons, after the man who laid the railroad. The name was quickly turned down due to another town on the Katy Line with the same label.  The Matson Brothers tried to stop the progress in this town, and thus the town was named “Defiance” because they defied the Matson’s and allowed progress to continue.

Defiance Schools

There are no local schools in Defiance due to the small nature of this community. Students living in this area attend the Warrenton school district. There are five public schools that are divided by age groups K-12th.  There are five elementary schools, two middles schools and one high school in Warrenton. Each of the elementary schools has around 450 students and the high school has 930.  The class sizes are rather small with 15 students per teacher.  By having smaller class sizes, Warrenton can ensure that their students are getting a quality education and get the one-on-one interaction that they need.

Contact us today at 314-310-9988 for more information about living in Defiance.

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